Complete Genome Sequence of an Atypical Dengue Virus Serotype 2 Lineage Isolated in Brazil

Felipe Scassi Salvador; Jaime Henrique Amorim; Rubens Prince Santos Alves; Sara A Pereira; Luis Carlos Souza Ferreira; Camila Malta Romano

doi:10.1128/genomeA.00779-15

Complete Genome Sequence of an Atypical Dengue Virus Serotype 2 Lineage Isolated in Brazil

Genome Announc. 2015 Jul 16;3(4):e00779-15. doi: 10.1128/genomeA.00779-15.

Authors

Felipe Scassi Salvador¹, Jaime Henrique Amorim², Rubens Prince Santos Alves², Sara A Pereira², Luis Carlos Souza Ferreira², Camila Malta Romano³

Affiliations

¹ São Paulo Institute of Tropical Medicine, University of São Paulo School of Medicine, São Paulo, Brazil.
² Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
³ São Paulo Institute of Tropical Medicine, University of São Paulo School of Medicine, São Paulo, Brazil cmromano@usp.br.

Abstract

Here, we report the complete polyprotein sequence of a dengue virus 2 strain isolated in Brazil. This virus belongs to the American genotype and has the ability to cause neurovirulence in immunocompetent adult mice. The data presented here may help understand the genetic determinants responsible for neurovirulence.