New metabolites from endolichenic fungus Pleosporales sp

Chem Biodivers. 2015 Jul;12(7):1095-104. doi: 10.1002/cbdv.201400279.

Abstract

Eight new metabolites were obtained from the culture of an endolichenic fungus, Pleosporales sp. Their structures were determined as three terphenyl derivatives, cucurbitarins A-C (1-3, resp.), two structurally related compounds, cucurbitarins D and E (4 and 5, resp.), two benzocoumarins, 3,10-dihydroxy-4,8-dimethoxy-6-methylbenzocoumarin (6) and 3,8,10-trihydroxy-4-methoxy-6-methylbenzocoumarin (7), as well as one cyclohexenone, (5R)-5-hydroxy-2,3-dimethylcyclohex-2-en-1-one (8), based on the spectroscopic data.

Keywords: Benzocoumarins; Cucurbitarins; Endolichenic fungi; Fungi; Pleosporales; Terphenyl derivatives.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Ascomycota / chemistry*
  • Ascomycota / metabolism*
  • Molecular Conformation
  • Terphenyl Compounds / chemistry
  • Terphenyl Compounds / isolation & purification
  • Terphenyl Compounds / metabolism*

Substances

  • Terphenyl Compounds