Abstract
On the basis of observational screening in conscious rats, the essential oil of Laurobasidium lauri seems to be the main agent responsible for the sedating and analgesic effects of this fungus. The inhibitory activity observed in isolated rat uterus with the butanol and alkaloid-rich fractions of this species appears to be related to a decrease in the calcium available for contraction.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Acetylcholine / pharmacology
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Animals
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Basidiomycota / analysis*
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Calcium Chloride / pharmacology
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Female
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In Vitro Techniques
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Male
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Mice
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Oils, Volatile / pharmacology*
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Oxytocin / pharmacology
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Potassium / pharmacology
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Rats
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Serotonin / pharmacology
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Spain
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Uterine Contraction / drug effects
Substances
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Oils, Volatile
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Serotonin
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Oxytocin
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Calcium Chloride
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Acetylcholine
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Potassium