[Biomimetic sensors in biomedical research]

Med Sci (Paris). 2015 Jun-Jul;31(6-7):654-9. doi: 10.1051/medsci/20153106019. Epub 2015 Jul 7.
[Article in French]

Abstract

The recent research on both the synthesis of membrane proteins by cell-free systems and the reconstruction of planar lipid membranes, has led to the development of a cross-technology to produce biosensors or filters. Numerous biomimetic membranes are currently being standardized and used by the industry, such as filters containing aquaporin for water desalination, or used in routine at the laboratory scale, for example the bacteriorhodopsin as a light sensor. In the medical area, several fields of application of these biomimetic membranes are under consideration today, particularly for the screening of therapeutic molecules and for the developing of new tools in diagnosis, patient monitoring and personalized medicine.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Animals
  • Biomedical Research / instrumentation*
  • Biomimetic Materials*
  • Biosensing Techniques / instrumentation*
  • Humans
  • Lipid Bilayers
  • Membrane Proteins / biosynthesis
  • Membranes, Artificial

Substances

  • Lipid Bilayers
  • Membrane Proteins
  • Membranes, Artificial