Unfolded protein response in plants: one master, many questions

Cristina Ruberti; Sang-Jin Kim; Giovanni Stefano; Federica Brandizzi

doi:10.1016/j.pbi.2015.05.016

Unfolded protein response in plants: one master, many questions

Curr Opin Plant Biol. 2015 Oct:27:59-66. doi: 10.1016/j.pbi.2015.05.016. Epub 2015 Jul 5.

Authors

Cristina Ruberti¹, Sang-Jin Kim¹, Giovanni Stefano¹, Federica Brandizzi²

Affiliations

¹ Plant Research Laboratory, Department of Energy-Michigan State University, East Lansing, MI, USA; Department of Plant Biology, Michigan State University, East Lansing, MI, USA.
² Plant Research Laboratory, Department of Energy-Michigan State University, East Lansing, MI, USA; Department of Plant Biology, Michigan State University, East Lansing, MI, USA. Electronic address: fb@msu.edu.

Abstract

To overcome endoplasmic reticulum (ER) stress, ER-localized stress sensors actuate distinct downstream organelle-nucleus signaling pathways to invoke a cytoprotective response, known as the unfolded protein response (UPR). Compared to yeast and metazoans, plant UPR studies are more recent but nevertheless fascinating. Here we discuss recent discoveries in plant UPR, highlight conserved and unique features of the plant UPR as well as critical yet-open questions whose answers will likely make significant contributions to the understanding plant ER stress management.

Publication types

Research Support, N.I.H., Extramural
Research Support, U.S. Gov't, Non-P.H.S.
Review

MeSH terms

Endoplasmic Reticulum Stress*
Gene Expression Regulation, Plant*
Plant Physiological Phenomena*
Unfolded Protein Response*

Abstract

Publication types

MeSH terms

Grants and funding