A Novel pseudo-Four-Component Domino Reaction for the Synthesis of Naphtho[2,1-b]furan-2(1H)-ones Using a Nanocatalyst

ACS Comb Sci. 2015 Aug 10;17(8):452-8. doi: 10.1021/acscombsci.5b00018. Epub 2015 Jul 20.

Abstract

In this article, an original one-pot method is utilized to synthesize a variety of derivatives of naphtho[2,1-b]furan-2(1H)-one via a pseudo-four-component domino reaction of aryl aldehydes, acetic anhydride, hippuric acids, and 2-naphthols catalyzed by HSW@SPIONs. This reaction illustrates an array of attractive features including, with particular interest in this report, a convenient and unique process of creating and utilizing a powerful recyclable nanocatalyst.

Keywords: domino reaction; heterocycles; multicomponent reaction; nanocatalyst; naphthofuran; tungstosilicic acid hydrate.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acetic Anhydrides / chemistry*
  • Aldehydes / chemistry*
  • Catalysis
  • Hippurates / chemistry*
  • Lactones / chemical synthesis*
  • Lactones / chemistry
  • Magnetite Nanoparticles / chemistry*
  • Molecular Structure
  • Naphthalenes / chemical synthesis*
  • Naphthalenes / chemistry
  • Naphthols / chemistry*
  • Oxides / chemistry*
  • Silicon Dioxide / chemistry*
  • Tungsten Compounds / chemistry*

Substances

  • Acetic Anhydrides
  • Aldehydes
  • Hippurates
  • Lactones
  • Magnetite Nanoparticles
  • Naphthalenes
  • Naphthols
  • Oxides
  • Tungsten Compounds
  • acetic anhydride
  • Silicon Dioxide
  • 2-naphthol
  • hippuric acid