Tityus bahiensis scorpion venom injected to dams during pregnancy affects some cytokines of fetuses

Toxicon. 2015 Sep:103:114-8. doi: 10.1016/j.toxicon.2015.06.023. Epub 2015 Jun 30.

Abstract

Due to the high incidence of scorpion stings in Brazil, pregnant women are among the possible victims. Cytokines are important during the pregnancy, and scorpion venoms can change their release. We evaluated the levels of some cytokines in the fetuses after the treatment of pregnant rats with the Tityus bahiensis scorpion venom. The concentration of some of them is altered and can be responsible for the effects previously observed on innate reflexes, and the physical and behavioral development of the offspring.

Keywords: Cytokines; Fetuses; Pregnancy; Scorpion venom; Tityus bahiensis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Brazil / epidemiology
  • Cytokines / blood*
  • Female
  • Fetus / drug effects*
  • Fetus / metabolism
  • Incidence
  • Male
  • Pregnancy
  • Rats
  • Rats, Wistar
  • Scorpion Stings / epidemiology
  • Scorpion Venoms / toxicity*
  • Scorpions / metabolism*

Substances

  • Cytokines
  • Scorpion Venoms