A new steroid from the Red Sea soft coral Lobophytum lobophytum

Mohamed-Elamir F Hegazy; Tarik A Mohamed; Abdelsamed I Elshamy; Abuzeid A Hassanien; Nahla S Abdel-Azim; Mohamed A Shreadah; Ibrahim I Abdelgawad; Eman M Elkady; Paul W Paré

doi:10.1080/14786419.2015.1046871

A new steroid from the Red Sea soft coral Lobophytum lobophytum

Nat Prod Res. 2016;30(3):340-4. doi: 10.1080/14786419.2015.1046871. Epub 2015 Jul 2.

Authors

Mohamed-Elamir F Hegazy¹, Tarik A Mohamed¹, Abdelsamed I Elshamy², Abuzeid A Hassanien³, Nahla S Abdel-Azim⁴, Mohamed A Shreadah⁵, Ibrahim I Abdelgawad³, Eman M Elkady⁵, Paul W Paré⁶

Affiliations

¹ a Phytochemistry Department and Center of Excellence for Advanced Sciences , National Research Centre , P.O. 12622, 33 El Bohouth st. (Former El Tahrir st.) Dokki, Giza , Egypt.
² b Natural Compounds Chemistry Department , National Research Centre , P.O. 12622, 33 El Bohouth st. (Former El Tahrir st.) Dokki, Giza , Egypt.
³ c Department of Chemistry , Faculty of Science, Suez University , Egypt.
⁴ d Phytochemistry Department , National Research Centre , P.O. 12622, 33 El Bohouth st. (Former El Tahrir st.) Dokki, Giza , Egypt.
⁵ e National Institute of Oceanography & Fisheries , Alexandria , Egypt.
⁶ f Department of Chemistry and Biochemistry , Texas Tech University , Lubbock , TX 79409 , USA.

PMID: 26134487
DOI: 10.1080/14786419.2015.1046871

Abstract

Chemical investigation of the soft coral Lobophytum lobophytum collected from the Red Sea led to the isolation of a new compound gorgostan-5,25-dien-3β-ol (1), and two known compounds gorgosterol (2), and alismol (3). Structures were elucidated by employing extensive NMR and HR-ESI-MS experiments.

Keywords: Lobophytum lobophytum; Red Sea; sesquiterpene; steriods.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Anthozoa / chemistry*
Cholesterol / analogs & derivatives
Cholesterol / isolation & purification
Indian Ocean
Magnetic Resonance Spectroscopy
Molecular Structure
Sesquiterpenes / isolation & purification
Spectrometry, Mass, Electrospray Ionization
Steroids / chemistry*
Steroids / isolation & purification

Substances

Sesquiterpenes
Steroids
gorgostan-5,25-dien-3'-ol
gorgosterol
alismol
Cholesterol