Surgical treatment in spine Paget's disease: a systematic review

Eur J Orthop Surg Traumatol. 2016 Jan;26(1):27-30. doi: 10.1007/s00590-015-1659-5. Epub 2015 Jul 1.

Abstract

Paget's disease of bone (PDB) is a disease characterized by a disorder in the bone metabolism. The spine is the second region affected after the pelvis. Surgical treatment is reserved for cases refractory to medical treatment. We performed a systematic review of patients with Paget disease of bone affecting the spine, treated surgically in the last 30 years. The main objective of the review is to find out indications for surgery, outcomes of these patients and also the standard perioperative management.

Keywords: Paget’s disease; Spine; Surgery.

Publication types

  • Review
  • Systematic Review

MeSH terms

  • Bone Cements / therapeutic use
  • Bone Density Conservation Agents / therapeutic use
  • Cervical Vertebrae / surgery
  • Diphosphonates / therapeutic use
  • Humans
  • Lumbar Vertebrae / surgery
  • Osteitis Deformans / surgery*
  • Polymethyl Methacrylate / therapeutic use
  • Postoperative Complications / etiology
  • Preoperative Care
  • Spinal Diseases / surgery*
  • Thoracic Vertebrae / surgery
  • Treatment Outcome

Substances

  • Bone Cements
  • Bone Density Conservation Agents
  • Diphosphonates
  • Polymethyl Methacrylate