Osteogenesis imperfecta and rapid maxillary expansion: Report of 3 patients

Gaetano Ierardo; Francesca Calcagnile; Valeria Luzzi; Barbara Ladniak; Maurizio Bossu; Mauro Celli; Anna Zambrano; Lorenzo Franchi; Antonella Polimeni

doi:10.1016/j.ajodo.2015.01.029

Osteogenesis imperfecta and rapid maxillary expansion: Report of 3 patients

Am J Orthod Dentofacial Orthop. 2015 Jul;148(1):130-7. doi: 10.1016/j.ajodo.2015.01.029.

Authors

Gaetano Ierardo¹, Francesca Calcagnile², Valeria Luzzi¹, Barbara Ladniak¹, Maurizio Bossu¹, Mauro Celli³, Anna Zambrano³, Lorenzo Franchi⁴, Antonella Polimeni⁵

Affiliations

¹ Assistant professor, Department of Oral and Maxillofacial Sciences, Pediatric Dentistry, Sapienza University of Rome, Rome, Italy.
² Postgraduate student, Department of Oral and Maxillofacial Sciences, Pediatric Dentistry, Sapienza University of Rome, Rome, Italy.
³ Assistant professor, Department of Pediatrics and Pediatric Neuropsychiatry, Center for Congenital Osteodystrophy, Sapienza University of Rome, Rome, Italy.
⁴ Assistant professor, Department of Surgery and Translational Medicine, University of Florence, Florence, Italy; Thomas M. Graber Visiting Scholar, Department of Orthodontics and Pediatric Dentistry, School of Dentistry, University of Michigan, Ann Arbor, Mich. Electronic address: lorenzo.franchi@unifi.it.
⁵ Professor and chair, Department of Oral and Maxillofacial Sciences, Pediatric Dentistry, Sapienza University of Rome, Rome, Italy.

PMID: 26124036
DOI: 10.1016/j.ajodo.2015.01.029

Abstract

Introduction: The aim of this study was to analyze the effects of orthopedic therapy with rapid maxillary expansion (RME) in growing patients affected by osteogenesis imperfecta and treated with bisphosphonates.

Methods: Three boys with osteogenesis imperfecta (mean age, 10.6 years) were treated with RME. They all had treatment with quarterly intravenous infusions of bisphosphonates. They were in either the early or the late mixed dentition and had indications for RME. The expansion screw was activated twice daily until correction of the transverse relationships was achieved. The retention period with the expander in place was 6 months. In 2 Class III patients, RME was associated with the use of a facemask. In all patients, occlusal radiographs were taken at the end of active RME therapy to assess the opening of the midpalatal suture and 1 year after the end of active expansion therapy to evaluate the reossification and reorganization of the midpalatal suture.

Results: In all patients, the opening of the midpalatal suture and the healing with reorganization of the midpalatal suture were documented with the occlusal radiographs. No complications were found after a 1-year follow-up.

Conclusions: In growing patients affected by osteogenesis imperfecta and treated with bisphosphonates, it is possible to perform RME with a standard protocol with no complications after a 1-year follow-up.

Publication types

Case Reports

MeSH terms

Adolescent
Cephalometry
Child
Humans
Male
Osteogenesis Imperfecta / pathology*
Palatal Expansion Technique*