Dietary supplemental vitamin B6 increases carnosine and anserine concentrations in the heart of rats

Sofya Suidasari; Tomoko Hasegawa; Noriyuki Yanaka; Norihisa Kato

doi:10.1186/s40064-015-1074-8

Dietary supplemental vitamin B6 increases carnosine and anserine concentrations in the heart of rats

Springerplus. 2015 Jun 19:4:280. doi: 10.1186/s40064-015-1074-8. eCollection 2015.

Authors

Sofya Suidasari¹, Tomoko Hasegawa¹, Noriyuki Yanaka¹, Norihisa Kato¹

Affiliation

¹ Graduate School of Biosphere Science, Hiroshima University, Higashi-Hiroshima, 739-8528 Japan.

Abstract

This study was performed to examine the effect of dietary level of vitamin B6 on the concentrations of carnosine and anserine, antioxidants, in the heart of rats. Analysis using UPLC-MS/MS showed that the concentrations of these dipeptides in the 7 and 35 mg pyridoxine HCl/kg groups were significantly higher than those in the 1 mg pyridoxine HCl/kg group, implying the novel role of dietary vitamin B6 as a determinant of the dipeptides favorable for heart.

Keywords: Anserine; Carnosine; Heart; UPLC–MS/MS; Vitamin B6.

Publication types

Case Reports