Identification and practical management of latex allergy in occupational settings

Expert Rev Clin Immunol. 2015;11(9):977-92. doi: 10.1586/1744666X.2015.1059754. Epub 2015 Jun 23.

Abstract

Allergy to natural rubber latex (NRL) from Hevea brasiliensis is a relevant occupational health hazard. The use of gloves and products manufactured with latex and environmental allergen exposure in the work environment are risks factors for the development of occupational allergy among different job categories. Healthcare workers have been the most commonly affected, but other professions with exposure to latex products such as hairdressers, cleaners, food handlers and those making natural rubber latex (NRL) products are also at risk of developing occupational allergy. Clinical manifestations of IgE-mediated latex allergy can range from troublesome skin disorders to life-threatening systemic reactions. It is very important to identify the occupational allergic diseases in their early stages in order to implement avoidance strategies. For this purpose, the interventions for prevention should emphasize the importance of latex allergy awareness and surveillance among exposed workforces.

Keywords: component-resolved diagnosis; immunotherapy; latex allergens; latex allergy; natural rubber latex; occupational allergy; occupational asthma; specific IgE antibodies.

Publication types

  • Review

MeSH terms

  • Allergens / immunology
  • Dermatitis, Allergic Contact / diagnosis
  • Dermatitis, Allergic Contact / immunology
  • Dermatitis, Allergic Contact / therapy*
  • Dermatitis, Occupational / diagnosis
  • Dermatitis, Occupational / immunology
  • Dermatitis, Occupational / therapy*
  • Hevea / chemistry
  • Humans
  • Immunotherapy / methods*
  • Immunotherapy / trends
  • Latex Hypersensitivity / diagnosis
  • Latex Hypersensitivity / immunology
  • Latex Hypersensitivity / therapy*
  • Occupational Exposure / analysis
  • Occupational Exposure / prevention & control*
  • Rubber / chemistry
  • Treatment Outcome

Substances

  • Allergens
  • Rubber