Multicenter evaluation of BD Veritor System and RSV K-SeT for rapid detection of respiratory syncytial virus in a diagnostic laboratory setting

Diagn Microbiol Infect Dis. 2015 Sep;83(1):37-40. doi: 10.1016/j.diagmicrobio.2015.05.012. Epub 2015 May 27.

Abstract

The recently introduced BD Veritor System RSV laboratory kit (Becton Dickinson, Sparks, MD, USA) with automatic reading was evaluated and compared with the RSV K-SeT (Coris BioConcept, Gembloux, Belgium) for the detection of respiratory syncytial virus (RSV) using 248 nasopharyngeal aspirates of children younger than 6 years old with respiratory tract infection. Compared to reverse transcriptase polymerase chain reaction as gold standard, both tests had an identical sensitivity of 78.1% and a specificity of 96.8% and 95.8% for the BD Veritor System and RSV K-SeT, respectively. Both antigen tests can be used to reliably confirm RSV in young children. However, a negative result does not definitively exclude the presence of RSV.

Keywords: Antigen test; BD Veritor System; RSV; RSV K-SeT; RSV Respi-Strip.

Publication types

  • Comparative Study
  • Evaluation Study
  • Multicenter Study

MeSH terms

  • Animals
  • Antigens, Viral / analysis
  • Child
  • Child, Preschool
  • Clinical Laboratory Techniques / methods*
  • Clinical Trials as Topic
  • Diagnostic Tests, Routine / methods*
  • Female
  • Humans
  • Infant
  • Male
  • Nasopharynx / virology
  • Predictive Value of Tests
  • Prospective Studies
  • Respiratory Syncytial Virus Infections / diagnosis*
  • Respiratory Syncytial Viruses / isolation & purification*
  • Sensitivity and Specificity

Substances

  • Antigens, Viral