Draft Genome Sequences of Clinical Daptomycin-Nonsusceptible Methicillin-Resistant Staphylococcus aureus Strain APS211 and Its Daptomycin-Susceptible Progenitor APS210

David R Cameron; Jhih-Hang Jiang; Iain J Abbott; Denis W Spelman; Anton Y Peleg

doi:10.1128/genomeA.00568-15

Draft Genome Sequences of Clinical Daptomycin-Nonsusceptible Methicillin-Resistant Staphylococcus aureus Strain APS211 and Its Daptomycin-Susceptible Progenitor APS210

Genome Announc. 2015 Jun 11;3(3):e00568-15. doi: 10.1128/genomeA.00568-15.

Authors

David R Cameron¹, Jhih-Hang Jiang¹, Iain J Abbott, Denis W Spelman, Anton Y Peleg²

Affiliations

¹ Department of Microbiology, Monash University, Melbourne, Australia.
² anton.peleg@monash.edu.

Abstract

To assess the genetic factors contributing to daptomycin resistance in Staphylococcus aureus, the draft genome of a clinically derived daptomycin-nonsusceptible isolate APS211 was generated and compared to the draft sequence of its susceptible progenitor strain APS210. Four genetic differences were identified including a previously described mutation within the mprF gene.