Complete genome sequence of Lactobacillus helveticus MB2-1, a probiotic bacterium producing exopolysaccharides

Wei Li; Xiudong Xia; Xiaohong Chen; Xin Rui; Mei Jiang; Qiuqin Zhang; Jianzhong Zhou; Mingsheng Dong

doi:10.1016/j.jbiotec.2015.05.021

Complete genome sequence of Lactobacillus helveticus MB2-1, a probiotic bacterium producing exopolysaccharides

J Biotechnol. 2015 Sep 10:209:14-5. doi: 10.1016/j.jbiotec.2015.05.021. Epub 2015 Jun 9.

Authors

Wei Li¹, Xiudong Xia², Xiaohong Chen¹, Xin Rui¹, Mei Jiang¹, Qiuqin Zhang¹, Jianzhong Zhou², Mingsheng Dong³

Affiliations

¹ College of Food Science and Technology, Nanjing Agricultural University, Nanjing, Jiangsu 210095, PR China.
² Institute of Agro-Product Processing, Jiangsu Academy of Agricultural Sciences, Nanjing, Jiangsu 210095, PR China.
³ College of Food Science and Technology, Nanjing Agricultural University, Nanjing, Jiangsu 210095, PR China. Electronic address: dongms@njau.edu.cn.

PMID: 26065338
DOI: 10.1016/j.jbiotec.2015.05.021

Abstract

Lactobacillus helveticus MB2-1 is a probiotic bacterium producing exopolysaccharides (EPS), which was isolated from traditional Sayram ropy fermented milk in southern Xinjiang, China. The genome consists of a circular 2,084,058bp chromosome with no plasmid. The genome sequence indicated that this strain includes a 15.20kb gene cluster involved in EPS biosynthesis. Genome sequencing information has provided the basis for understanding the potential molecular mechanism behind the EPS production.

Keywords: Exopolysaccharides (EPS); Genome; Lactobacillus helveticus; Probiotic.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Cultured Milk Products / microbiology
Genome Size
Genome, Bacterial*
Lactobacillus helveticus / genetics*
Lactobacillus helveticus / isolation & purification
Lactobacillus helveticus / metabolism
Multigene Family
Polysaccharides, Bacterial / metabolism
Probiotics
Sequence Analysis, DNA / methods*

Substances

Polysaccharides, Bacterial