This review presents in a comprehensive ways the chemical methods used to functionalize gold nanoparticles with focus on anti-cancer applications. The review covers the parameters required for the synthesis gold nanoparticles with defined shapes and sizes, method for targeted delivery in tumours, and selected examples of anti-cancers compounds delivered with gold nanoparticles. A short survey of bioassays for oncology based on gold nanoparticles is also presented.
Keywords: Cancer; Diagnostic; Gold; Nanoparticles; Therapy.
Copyright © 2015 Elsevier Masson SAS. All rights reserved.