DNA-functionalized upconversion nanoparticles as biosensors for rapid, sensitive, and selective detection of Hg(2+) in complex matrices

Analyst. 2015 Aug 7;140(15):4987-90. doi: 10.1039/c5an00635j.

Abstract

We have developed a facile one-step approach to make hydrophilic and DNA-functionalizable upconversion nanoparticles (UCNPs), which are used to act as a biosensor for determining Hg(2+) in complex matrices. The proposed approach is simple and exhibits low background interference, high sensitivity and rapid response.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biosensing Techniques / economics
  • Biosensing Techniques / methods*
  • Cations, Divalent / analysis
  • Cations, Divalent / urine
  • DNA / chemistry*
  • Drinking Water / analysis
  • Humans
  • Limit of Detection
  • Luminescence
  • Mercury / analysis*
  • Mercury / urine*
  • Nanoparticles / chemistry*
  • Nanoparticles / ultrastructure
  • Rivers / chemistry
  • Spectrometry, Fluorescence / methods
  • Water Pollutants, Chemical / analysis*
  • Water Pollutants, Chemical / urine*

Substances

  • Cations, Divalent
  • Drinking Water
  • Water Pollutants, Chemical
  • DNA
  • Mercury