The role of PET/CT in the evaluation of patients affected by limbic encephalitis: A systematic review of the literature

J Neuroimmunol. 2015 Jul 15:284:44-8. doi: 10.1016/j.jneuroim.2015.05.002. Epub 2015 May 1.

Abstract

Autoimmune limbic encephalitis (LE) is a rare disorder affecting the medial temporal lobe of the brain. Although brain Magnetic Resonance (MR) has been widely evaluated and is currently considered essential in the suspicion of LE, Positron Emission Tomography/Computed Tomography (PET/CT) has been demonstrated to be useful also in the evaluation of brain inflammatory diseases such as encephalitis. We therefore aim to review the current literature about the role of PET/CT in the evaluation of patients affected by LE.

Keywords: Brain MR; Limbic encephalitis; NMDAR antibodies; PET/CT.

Publication types

  • Review
  • Systematic Review

MeSH terms

  • Brain* / diagnostic imaging
  • Brain* / pathology
  • Databases, Bibliographic / statistics & numerical data
  • Fluorodeoxyglucose F18
  • Humans
  • Limbic Encephalitis / diagnosis*
  • Positron-Emission Tomography*
  • Tomography, X-Ray Computed*

Substances

  • Fluorodeoxyglucose F18