Abstract
Supramolecular aggregates formed through the association of an amphiphilic tetra-O-butylsulfonate calix[4]arene 1 were investigated in aqueous solution by a combination of different techniques (NMR, DLS and AFM). The ability of the micellar aggregates of calixarene 1 to increase the solubility of poorly water-soluble drugs was studied.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anions / chemistry
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Calixarenes / chemistry*
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Dynamic Light Scattering
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Flurbiprofen / chemistry*
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Magnetic Resonance Spectroscopy
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Micelles
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Microscopy, Atomic Force
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Molecular Structure
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Naproxen / chemistry*
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Solubility
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Surface-Active Agents / chemistry
Substances
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Anions
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Micelles
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Surface-Active Agents
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p-tert-butylcalix(4)arene tetra-O-butylsulfonate
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Calixarenes
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Naproxen
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Flurbiprofen