Flavones from Cassia siamea and their anti-tobacco mosaic virus activity

J Asian Nat Prod Res. 2015;17(9):882-7. doi: 10.1080/10286020.2015.1034114. Epub 2015 May 19.

Abstract

Two new flavones, siameflavones A and B (1 and 2), together with five known flavones (3-7) were isolated from the stem of Cassia siamea. Their structures were elucidated by spectroscopic methods including extensive 1D and 2D NMR techniques. Compounds 1-5 were evaluated for their anti-tobacco mosaic virus (Anti-TMV) activity. The results showed that compounds 1-5 showed weak anti-TMV activity with inhibition rates in the range of 11.6-18.5%.

Keywords: Leguminosae; Cassia siamea; anti-tobacco mosaic virus; flavones.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antiviral Agents / chemistry
  • Antiviral Agents / isolation & purification*
  • Antiviral Agents / pharmacology*
  • Cassia / chemistry*
  • Flavones / chemistry
  • Flavones / isolation & purification*
  • Flavones / pharmacology*
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Plant Leaves / chemistry
  • Plant Stems / chemistry
  • Tobacco Mosaic Virus / drug effects*

Substances

  • Antiviral Agents
  • Flavones
  • siameflavone A
  • siameflavone B