Under stressful conditions, organisms often try to detoxify by mobilizing certain energy sources with costs to various functions, e.g. growth or reproduction. Cellular energy allocation (CEA) is a commonly used methodology to evaluate the energetic status of an organism. In the present study, the effects of copper (Cu) and silver (Ag) were evaluated on the total energy budget of Enchytraeus crypticus (Oligochaeta) over periods of exposure (0-2, 2-4 and 4-8 days). The parameters measured were the total energy reserves available (protein, carbohydrate and lipid budgets) and the energy consumption (based on electron transport system activity) being further integrated to obtain the CEA. Results showed that Enchytraeids responded differently to Ag and Cu, mobilizing lipids and proteins in response to Ag and carbohydrates and proteins in response to Cu. Overall, it was possible to distinguish between effect concentrations (reproduction effect concentrations-EC10 and EC50), with EC10 causing an increase in energy consumption (Ec); while for the EC50, the increase in Ec is followed by a steep decrease in Ec, with a corresponding decrease in CEA in the longer exposure periods. These results could be linked with effects at higher levels of biological organization (effects on reproduction) providing evidences that CEA can be used as faster and sensitive endpoints towards metal exposure in E. crypticus.