Mononostril endoscopic transsphenoidal approach to sellar and peri-sellar lesions: Personal experience and literature review

Br J Neurosurg. 2015;29(4):532-7. doi: 10.3109/02688697.2015.1014997. Epub 2015 May 12.

Abstract

Objective: The endonasal endoscopic approach to skull base is still under investigation. The main goal is the minimal invasive approach to pathologies with a better rate of resection without retraction of the brain tissue. Here, the authors report their technique of transnasal endoscopic neurosurgery using a mononostril approach and its development.

Methods: The supplementary video demonstrates the different steps of the mononostril approach and resection of a pituitary adenoma. All video-recorded procedures that were carried out between 2000 and 2013 using this technique were analysed. The patients were followed prospectively.

Results: Visualization and handling were good in 246/251 (98%). In three cases, we had to switch to microscopy because of severe bleeding of the cavernous sinus. On follow-up, magnetic resonance imaging revealed radical tumour resection in 92% of all cases when intended. There was no mortality, and the low complication rate was remarkable.

Conclusion: Our mononostril approach of transnasal transsphenoidal surgery shows better results compared with previously published reports in regards to radicality, low cerebrospinal fluid leaks and morbidity. The very low rate of nasal complains is particularly remarkable.

Keywords: anterior skull base; endoscopy; pituitary surgery; transsphenoidal approach.

Publication types

  • Review

MeSH terms

  • Adenoma / surgery*
  • Adolescent
  • Adult
  • Aged
  • Female
  • Humans
  • Male
  • Middle Aged
  • Natural Orifice Endoscopic Surgery / adverse effects
  • Natural Orifice Endoscopic Surgery / methods*
  • Neuroendoscopy / adverse effects
  • Neuroendoscopy / methods*
  • Pituitary Neoplasms / surgery*
  • Sella Turcica / pathology
  • Sella Turcica / surgery*
  • Sphenoid Sinus / surgery
  • Treatment Outcome
  • Young Adult