Hyperglycemia management in patients admitted to internal medicine in Spain: A point-prevalence survey examining adequacy of glycemic control and guideline adherence

Eur J Intern Med. 2015 Jul;26(6):392-8. doi: 10.1016/j.ejim.2015.04.020. Epub 2015 May 8.

Abstract

Aims: Despite the increasing prevalence of hospitalized diabetic patients, there are few studies that evaluate the glycemic control and the rate of adherence to clinical practice guidelines for glucose monitoring and management in the hospital setting.

Methods: Crossover study using one-day surveys of all inpatients admitted to internal medicine wards from voluntary participating hospitals across Spain. Retrospective review of medical records was used to identify patients with hyperglycemia, causes for hospitalization, patients' demographic characteristics, appropriateness of glycemic monitoring and treatment during hospitalization.

Results: Among 5439 hospitalized patients studied there were 1000 (18.4%) with hyperglycemia in 111 participating hospitals. Patients mean age was 76.0±8.5 years (51.6% male). On admission, 91% had known diabetes (disease duration of 10.9±8.5 years), 5% had unknown diabetes and 4% had stress hyperglycemia. The comorbidity index (Charslon score) was 4 (interquartile range: 2 to 6) and 31% showed a high level of disability (Rankin scale). Main infringement in the process of care included lack of a recent HbA1c value (43.7%), use of sliding scale insulin therapy (20.7%), use of oral antidiabetic agents (8.9%), and less than three bedside point-of-care (POC) blood glucose test per day (17%). Glycemic target pre-meal and bedtime were achieved in 47% to 79.5% of POC. The rates of hypoglycemia (<70 mg/dL and <50mg/dL) were 10.3% and 2.4%, respectively.

Conclusions: Our results suggest that there is an important gap between the clinical guidelines and both the management and the grade of glycemic control of diabetic inpatients.

Keywords: Diabetes mellitus; Guideline; Hospitalization; Hypoglycemic agents; Insulin; Point-prevalence.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Cross-Sectional Studies
  • Diet / statistics & numerical data
  • Female
  • Glycated Hemoglobin / analysis
  • Guideline Adherence / statistics & numerical data*
  • Humans
  • Hyperglycemia / drug therapy
  • Hyperglycemia / epidemiology*
  • Hyperglycemia / therapy
  • Hypoglycemic Agents / therapeutic use
  • Insulin / therapeutic use
  • Internal Medicine / standards
  • Internal Medicine / statistics & numerical data
  • Male
  • Middle Aged
  • Prevalence
  • Spain / epidemiology
  • Young Adult

Substances

  • Glycated Hemoglobin A
  • Hypoglycemic Agents
  • Insulin
  • hemoglobin A1c protein, human