Abstract
Cl(-) transporters that bear a terminal ethynyl group were synthesized; they consist of non-pyrrolic hydrogen bond motifs such as phenolic OH, amide NH, and triazole CH. The ethynyl group of these non-pyrrolic analogs plays an important role in chloride efflux and they exhibit no significant cytotoxic activity.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Acetylene / analogs & derivatives*
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Acetylene / chemistry
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Ion Transport
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Models, Biological*
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Molecular Structure
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Organic Anion Transporters / chemical synthesis
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Organic Anion Transporters / chemistry
Substances
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Organic Anion Transporters
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phenylacetylene
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Acetylene