Abstract
The mitochondrial contact site and cristae organizing system (MICOS) complex is essential for normal mitochondria biogenesis and morphology. In this issue, Bohnert et al. (2015) and Barbot et al. (2015) demonstrate that a MICOS core subunit, Mic10, is crucial for mitochondrial cristae formation by forming oligomers at the cristae junctions.
Copyright © 2015 The Authors. Published by Elsevier Inc. All rights reserved.
Publication types
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Research Support, Non-U.S. Gov't
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Comment
MeSH terms
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Membrane Proteins / metabolism*
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Mitochondria / metabolism*
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Mitochondria / ultrastructure*
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Mitochondrial Membranes / metabolism*
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Mitochondrial Proteins / metabolism*
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Saccharomyces cerevisiae / cytology*
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Saccharomyces cerevisiae / metabolism*
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Saccharomyces cerevisiae Proteins / metabolism*
Substances
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Membrane Proteins
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Mitochondrial Proteins
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Saccharomyces cerevisiae Proteins