Abstract
A cyclic boronate structure was incorporated into Si-rhodamine to design a pH-activatable near-infrared (NIR) probe based on the reversible ring-opening process triggered by H(+). The probe showed general suitability of specific labelling of acidic lysosomes and tracking their pH changes in living cells.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Animals
-
Fluorescent Dyes / chemistry*
-
Fluorescent Dyes / metabolism
-
Hep G2 Cells
-
Humans
-
Hydrogen-Ion Concentration
-
Image Processing, Computer-Assisted / methods*
-
Lysosomes / metabolism*
-
Molecular Imaging
-
PC12 Cells
-
Rats
-
Rhodamines / chemistry*
-
Rhodamines / metabolism
-
Spectrometry, Fluorescence
-
Spectroscopy, Near-Infrared
-
Spironolactone / chemistry*
-
Spironolactone / metabolism
Substances
-
Fluorescent Dyes
-
Rhodamines
-
Spironolactone