Complete Genome Sequence of the Clinical Beijing-Like Strain Mycobacterium tuberculosis 323 Using the PacBio Real-Time Sequencing Platform

Juan Germán Rodríguez; Camilo Pino; Andreas Tauch; Martha Isabel Murcia

doi:10.1128/genomeA.00371-15

Complete Genome Sequence of the Clinical Beijing-Like Strain Mycobacterium tuberculosis 323 Using the PacBio Real-Time Sequencing Platform

Genome Announc. 2015 Apr 30;3(2):e00371-15. doi: 10.1128/genomeA.00371-15.

Authors

Juan Germán Rodríguez¹, Camilo Pino², Andreas Tauch³, Martha Isabel Murcia⁴

Affiliations

¹ Departamento de Microbiología, Facultad de Medicina, Grupo MICOBAC-UN, Universidad Nacional de Colombia, Sede Bogotá, Colombia.
² Facultad de Ingeniería, Grupo BioLISI, Universidad Nacional de Colombia, Sede Bogotá, Colombia.
³ Institut für Genomforschung und Systembiologie, Centrum für Biotechnology (CeBiTec), Universität Bielefeld, Bielefeld, Germany.
⁴ Departamento de Microbiología, Facultad de Medicina, Grupo MICOBAC-UN, Universidad Nacional de Colombia, Sede Bogotá, Colombia mimurciaa@unal.edu.co.

Abstract

We report here the whole-genome sequence of the multidrug-resistant Beijing-like strain Mycobacterium tuberculosis 323, isolated from a 15-year-old female patient who died shortly after the initiation of second-line drug treatment. This strain is representative of the Beijing-like isolates from Colombia, where this lineage is becoming a public health concern.