Comparison of field-of-view (FOV) optimized and constrained undistorted single shot (FOCUS) with conventional DWI for the evaluation of prostate cancer

Clin Imaging. 2015 Sep-Oct;39(5):851-5. doi: 10.1016/j.clinimag.2015.03.004. Epub 2015 Mar 21.

Abstract

Objectives: Qualitative and quantitative comparison of the application value of diffusion-weighted imaging (DWI) magnetic resonance imaging based on field-of-view (FOV) optimized and constrained undistorted single shot (FOCUS) with the standard single-shot echo-planar imaging (ss-EPI) in patients with prostate cancer.

Methods: A total of 28 patients with 33 prostate cancers underwent ss-EPI and FOCUS DWI. Two independent readers assessed image studies.

Results: Image qualities of FOCUS were rated superior to ss-EPI (P<.001). The mean apparent diffusion coefficient value of 33 cancers was 974.030×10(-6)mm(2)/s and 941.727×10(-6)mm(2)/s, respectively, and the difference was statistically significant (t=2.579, P=.015).

Conclusions: FOCUS as a high-resolution DWI technique has potential clinical utility.

Keywords: Apparent diffusion coefficient; Diffusion-weighted magnetic resonance imaging; Echo-planar imaging; Prostate cancer.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Diffusion Magnetic Resonance Imaging / methods*
  • Echo-Planar Imaging / methods*
  • Feasibility Studies
  • Female
  • Humans
  • Male
  • Middle Aged
  • Prostatic Neoplasms / diagnosis*