Clinical outcomes of nonvariceal upper gastrointestinal bleeding in Kosova

Turk J Gastroenterol. 2014 Dec:25 Suppl 1:110-5. doi: 10.5152/tjg.2014.4351.

Abstract

Background/aims: The aim was to determine the sociodemographic and etiologic factors, endoscopic accuracy, treatment efficiency and clinical outcome of patients with nonvariceal upper gastrointestinal system bleeding in Kosova.

Materials and methods: We retrospectively evaluated patients who had applied to our Gastroenterology Department between January 2006 and December 2010.

Results: There were 460 eligible cases with mean age 56.85+16.18 years, while male /female ratio was 2.71/1. The greatest occurrence was at age group of 60-69 years (27.1 %). The most common clinical symptom was melena (62.6%). Comorbid diseases were present in 57, 6% of the patients. The percentage of patients using acetylsalicylic acid and /or other non-steroidal anti-inflammatory drugs was 43.7%. Five point two percent were using anticoagulants. Peptic ulcer was the main cause of bleeding (82.2%) and most of them were Forrest III (41.6%). Endoscopic treatment was performed in 90 patients, primary hemostasis was achieved in 96.7% while rebleeding developed in 10% of these patients. The average length of hospital stay was 9.29+5.58 (1-35) days. Rebleeding was reported in 4.1% of all patients while the overall mortality rate was 5.7%.

Conclusion: Age over 60 years, previous history of gastrointestinal bleeding, treatment with anticoagulants, low hemoglobin values at presentation (<7 g/dL), hematemesis, Forrest class, localization of lesion of bleeding, comorbidities, tachycardia, transfusion requirement>2 unit, type of treatment and time of endoscopy were predictors of poor outcome in study present.

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Anti-Inflammatory Agents, Non-Steroidal / adverse effects
  • Anticoagulants / adverse effects
  • Aspirin / adverse effects
  • Cross-Sectional Studies
  • Duodenal Diseases / epidemiology
  • Duodenal Diseases / etiology
  • Duodenal Diseases / therapy*
  • Esophageal Diseases / epidemiology
  • Esophageal Diseases / etiology
  • Esophageal Diseases / therapy*
  • Female
  • Hematemesis / epidemiology
  • Hematemesis / etiology
  • Hematemesis / therapy
  • Hemostasis, Endoscopic*
  • Humans
  • Kosovo / epidemiology
  • Length of Stay
  • Male
  • Melena / epidemiology
  • Melena / etiology
  • Melena / therapy
  • Middle Aged
  • Peptic Ulcer Hemorrhage / epidemiology
  • Peptic Ulcer Hemorrhage / etiology
  • Peptic Ulcer Hemorrhage / therapy*
  • Recurrence
  • Retrospective Studies
  • Risk Factors
  • Stomach Diseases / epidemiology
  • Stomach Diseases / etiology
  • Stomach Diseases / therapy*
  • Survival Rate
  • Treatment Outcome
  • Young Adult

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • Anticoagulants
  • Aspirin