Broadband miniature optical ultrasound probe for high resolution vascular tissue imaging

Biomed Opt Express. 2015 Mar 26;6(4):1502-11. doi: 10.1364/BOE.6.001502. eCollection 2015 Apr 1.

Abstract

An all-optical ultrasound probe for vascular tissue imaging was developed. Ultrasound was generated by pulsed laser illumination of a functionalized carbon nanotube composite coating on the end face of an optical fiber. Ultrasound was detected with a Fabry-Pérot (FP) cavity on the end face of an adjacent optical fiber. The probe diameter was < 0.84 mm and had an ultrasound bandwidth of ~20 MHz. The probe was translated across the tissue sample to create a virtual linear array of ultrasound transmit/receive elements. At a depth of 3.5 mm, the axial resolution was 64 µm and the lateral resolution was 88 µm, as measured with a carbon fiber target. Vascular tissues from swine were imaged ex vivo and good correspondence to histology was observed.

Keywords: (060.2380) Fiber optics sources and detectors; (110.2350) Fiber optics imaging; (110.5125) Photoacoustics; (170.0110) Imaging systems; (170.7170) Ultrasound.