Androgenic-anabolic activities of some new synthesized steroidal pyrane, pyridine and thiopyrimidine derivatives

Bioorg Khim. 2014 Sep-Oct;40(5):618-28. doi: 10.7868/s0132342314050017.

Abstract

In continuation of our previous work, fused steroidal derivatives with pyrane, pyridine, pyrimidine moieties were synthesized and evaluated as androgenic-anabolic agents. Some of the newly synthesized compounds are exhibited pronounced androgenic-anabolic activities.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anabolic Agents / administration & dosage
  • Anabolic Agents / chemical synthesis
  • Anabolic Agents / chemistry*
  • Animals
  • Humans
  • Molecular Structure
  • Muscles / drug effects
  • Pyridines / administration & dosage
  • Pyridines / chemical synthesis
  • Pyridines / chemistry*
  • Pyrimidines / administration & dosage
  • Pyrimidines / chemical synthesis
  • Pyrimidines / chemistry*
  • Rats
  • Steroids / administration & dosage
  • Steroids / chemical synthesis
  • Steroids / chemistry*
  • Structure-Activity Relationship

Substances

  • Anabolic Agents
  • Pyridines
  • Pyrimidines
  • Steroids
  • pyrimidine
  • pyridine