Chemical and pharmacological progress on polyacetylenes isolated from the family apiaceae

Chem Biodivers. 2015 Apr;12(4):474-502. doi: 10.1002/cbdv.201300396.

Abstract

This review presents an up-to-date survey of natural polyacetylenes isolated from the family Apiaceae, and their biosynthesis and biological activities up to May 2013, with 107 references. A total of 103 polyacetylenes from 72 species of 41 genera of Apiaceae have been isolated so far, among which falcarinol-type polyacetylenes are most widely distributed.

Keywords: Apiaceae; Biological activity; Biosynthesis; Polyacetylenes.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / pharmacology
  • Anti-Inflammatory Agents, Non-Steroidal / chemistry
  • Anti-Inflammatory Agents, Non-Steroidal / pharmacology
  • Antifungal Agents / chemistry
  • Antifungal Agents / pharmacology
  • Antineoplastic Agents, Phytogenic / chemistry
  • Antineoplastic Agents, Phytogenic / pharmacology
  • Apiaceae / chemistry*
  • Humans
  • Polyynes / chemistry*
  • Polyynes / isolation & purification
  • Polyynes / metabolism
  • Polyynes / pharmacology*

Substances

  • Anti-Bacterial Agents
  • Anti-Inflammatory Agents, Non-Steroidal
  • Antifungal Agents
  • Antineoplastic Agents, Phytogenic
  • Polyynes