How Salmonella survives the macrophage's acid attack

PLoS Biol. 2015 Apr 14;13(4):e1002117. doi: 10.1371/journal.pbio.1002117. eCollection 2015 Apr.

Abstract

Instead of combating the acidification of the host cell vacuole, Salmonella acidifies its own cytoplasm in response to the low extracellular pH, helping it to secrete effector molecules.

Publication types

  • Comment

MeSH terms

  • Acids / metabolism*
  • Bacterial Proteins / physiology*
  • Biosensing Techniques*
  • DNA, Bacterial / analysis*
  • Fluorescence Resonance Energy Transfer*
  • Macrophages / microbiology*
  • Salmonella / pathogenicity*

Substances

  • Acids
  • Bacterial Proteins
  • DNA, Bacterial