Targeted disruption of Rab10 causes early embryonic lethality

Protein Cell. 2015 Jun;6(6):463-467. doi: 10.1007/s13238-015-0150-8.

Authors

Pingping Lv^#^{1

2}, Yi Sheng^#^{1

3}, Zhenao Zhao⁴, Wei Zhao^{1

2}, Lusheng Gu^{1

3}, Tao Xu¹, Eli Song¹

Affiliations

¹ National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101 China.
² University of Chinese Academy of Sciences, Beijing, 100049 China.
³ College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, 430074 China.
⁴ State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101 China.

^# Contributed equally.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Cell Nucleus Size / genetics
Cell Proliferation / genetics
Embryo Loss / genetics*
Embryo Loss / pathology
Embryo, Mammalian / metabolism*
Embryo, Mammalian / pathology
Embryonic Stem Cells / cytology
Endoplasmic Reticulum / genetics
Homologous Recombination*
Mice
rab GTP-Binding Proteins / deficiency*
rab GTP-Binding Proteins / genetics
rab GTP-Binding Proteins / metabolism*

Substances

Rab10 protein, mouse
rab GTP-Binding Proteins