Introduction of 2-octyl cyanoacrylate (Dermabond®) for incisional hernia mesh repair

Yoshiyuki Saito; Keisuke Kubota; Akihiro Okada; Tomoaki Deguchi; Junko Kuroda; Nobuhiro Nitori; Tomohisa Kadomura; Masashi Yoshida; Masaki Kitajima

doi:10.1007/s00595-015-1161-z

Introduction of 2-octyl cyanoacrylate (Dermabond^®) for incisional hernia mesh repair

Surg Today. 2016 Jan;46(1):123-128. doi: 10.1007/s00595-015-1161-z. Epub 2015 Apr 10.

Authors

Yoshiyuki Saito¹, Keisuke Kubota², Akihiro Okada³, Tomoaki Deguchi³, Junko Kuroda³, Nobuhiro Nitori³, Tomohisa Kadomura³, Masashi Yoshida³, Masaki Kitajima³

Affiliations

¹ Department of Surgery Gastroenterology Center, International University of Health and Welfare Mita Hospital, 1-4-3, Mita, Minato-ku, Tokyo, 108-8329, Japan. yoshiyuksaito@gmail.com.
² Department of Surgery, St. Luke's International Hospital, 9-1, Akashi-cho, Chuo City, Tokyo, 104-8560, Japan.
³ Department of Surgery Gastroenterology Center, International University of Health and Welfare Mita Hospital, 1-4-3, Mita, Minato-ku, Tokyo, 108-8329, Japan.

PMID: 25860590
DOI: 10.1007/s00595-015-1161-z

Abstract

Purpose: We developed a new technique, sutureless mesh fixation, using 2-octyl cyanoacrylate (Dermabond^®, a surgical tissue adhesive) for incisional hernia repair. The objective of this article is to introduce the new technique and to examine whether the technique provides sufficient resistance to abdominal pressure.

Methods: We conducted two tests using a porcine model, a traction experiment and artificial pneumoperitoneum test. In the traction experiment, the adherence properties of Dermabond^® with mesh and peritoneum were examined using a tissue fragment from a pig. In the artificial pneumoperitoneum test, which used an incisional hernia porcine model, mesh was implanted on the peritoneum in the abdominal cavity with Dermabond^®. It was then determined whether sutureless mesh fixation could bear artificial abdominal air pressure.

Results: In the traction experiment, Dermabond^®, which bonded the mesh to the peritoneum, tolerated pressure up to 2.45 × 10³ mmHg. In the artificial pneumoperitoneum test, the mesh was strongly fastened to the peritoneum by means of only Dermabond^®, and there was little air circulation even without closing the wound over the mesh.

Conclusions: Sutureless mesh fixation with Dermabond^® is technically feasible and promises to provide sufficient resistance to abdominal pressure.

Keywords: 2-Octyl cyanoacrylate; Postoperative pain; Sutureless mesh fixation; Ventral hernia.