Abstract
A genomic analysis of heterogeneous colorectal tumor samples has uncovered interactions between immunophenotype and various aspects of tumor biology, with implications for informing the choice of immunotherapies for specific patients and guiding the design of personalized neoantigen-based vaccines.
MeSH terms
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Antigens, Neoplasm / genetics*
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Antigens, Neoplasm / immunology
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Colorectal Neoplasms / genetics
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Colorectal Neoplasms / immunology*
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Colorectal Neoplasms / therapy
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Humans
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Immunophenotyping
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Immunotherapy*
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Lymphocytes, Tumor-Infiltrating / immunology*
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Lymphocytes, Tumor-Infiltrating / pathology
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Tumor Escape / genetics
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Tumor Escape / immunology