Idiopathic Facial Aseptic Granuloma: Review of an Evolving Clinical Entity

Pediatr Dermatol. 2015 Jul-Aug;32(4):e136-9. doi: 10.1111/pde.12571. Epub 2015 Apr 6.

Abstract

Idiopathic facial aseptic granuloma (IFAG), originally termed pyodermite froide du visage, describes a generally asymptomatic facial nodule presenting in childhood with clinical resemblance to pyoderma or cystic, granulomatous, or vascular lesions. Clinical understanding is constantly evolving, with recent observations indicating that IFAG may represent a subtype of childhood rosacea. We present a case of IFAG associated with eyelid chalazions in a 19-month-old boy. Although his clinical course paralleled previously reported IFAG cases, we observed a unique ultrasound variation during initial diagnostic examination. Further delineation of clinical, imaging, and histologic properties of IFAG may reveal insights into etiologic associations and ideal management.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Anti-Infective Agents / therapeutic use
  • Biopsy
  • Chalazion / diagnosis
  • Diagnosis, Differential
  • Facial Dermatoses / diagnostic imaging*
  • Facial Dermatoses / drug therapy
  • Facial Dermatoses / pathology
  • Granuloma / diagnostic imaging*
  • Granuloma / drug therapy
  • Granuloma / pathology
  • Humans
  • Infant
  • Male
  • Metronidazole / therapeutic use
  • Rosacea / diagnosis
  • Skin / pathology
  • Ultrasonography

Substances

  • Anti-Infective Agents
  • Metronidazole