Novel insights into an "old" phenomenon: the no reflow

Alessandro Durante; Paolo G Camici

doi:10.1016/j.ijcard.2015.03.359

Novel insights into an "old" phenomenon: the no reflow

Int J Cardiol. 2015:187:273-80. doi: 10.1016/j.ijcard.2015.03.359. Epub 2015 Mar 26.

Authors

Alessandro Durante¹, Paolo G Camici²

Affiliations

¹ Ospedale Valduce, Como, Italy. Electronic address: durante.alessandro@gmail.com.
² Università Vita-Salute San Raffaele, Milan, Italy.

PMID: 25838230
DOI: 10.1016/j.ijcard.2015.03.359

Abstract

Coronary artery diseases and particularly acute myocardial infarction are the leading causes of mortality and morbidity in western countries. Despite the achievements of the last decades with the advent of double antiplatelet therapy, new antithrombotics and reperfusion strategies (either pharmacological or mechanical), many patients still have adverse cardiovascular events after ST-segment elevation acute myocardial infarction; at least some of these adverse events are related to the no reflow phenomenon that occurs after primary percutaneous coronary intervention. In our review we will discuss the various aspects of this phenomenon.

Keywords: Cardiac magnetic resonance; Microvascular obstruction; Myocardial infarction; No reflow; Percutaneous coronary intervention; STEMI.

Publication types

Review

MeSH terms

Humans
No-Reflow Phenomenon* / diagnosis
No-Reflow Phenomenon* / etiology
No-Reflow Phenomenon* / therapy
Risk Factors