Spontaneous ascitic fluid infection and bacteremia due to Yersinia pseudotuberculosis in a liver transplant patient

A Renvoisé; N Lemaitre; G Saintenoy; H Benosman; C Geffrier; L Epelboin; V Jarlier; T Poynard; D Thabut

doi:10.1016/j.ijid.2015.03.019

Spontaneous ascitic fluid infection and bacteremia due to Yersinia pseudotuberculosis in a liver transplant patient

Int J Infect Dis. 2015 May:34:122-5. doi: 10.1016/j.ijid.2015.03.019. Epub 2015 Mar 30.

Authors

A Renvoisé¹, N Lemaitre², G Saintenoy³, H Benosman⁴, C Geffrier⁴, L Epelboin⁵, V Jarlier⁶, T Poynard⁴, D Thabut⁴

Affiliations

¹ AP-HP, Hôpital Pitié-Salpêtrière, Centre National de Référence des Mycobactéries et de la Résistance des Mycobactéries aux Antituberculeux, Bactériologie-Hygiène, Paris, France; INSERM, U1135, Centre d'Immunologie et des Maladies Infectieuses, CIMI, team E13 (Bacteriology), Paris, France; Sorbonne Universités, UPMC Univ Paris 06, CR7, Centre d'Immunologie et des Maladies Infectieuses, CIMI, team E13 (Bacteriology), Paris, France. Electronic address: aurelie.renvoise@gmail.com.
² CHRU Lille, Laboratoire de Bactériologie-Hygiène, Lille, France; Université Lille Nord de France, Lille, France; INSERM U1019- UMR8204, F-59021 Lille, France.
³ AP-HP, Hôpital Pitié-Salpêtrière, Centre National de Référence des Mycobactéries et de la Résistance des Mycobactéries aux Antituberculeux, Bactériologie-Hygiène, Paris, France.
⁴ AP-HP, Hôpital Pitié-Salpêtrière, Department of Hepatogastroenterology, Paris.
⁵ AP-HP, Hôpital Pitié-Salpêtrière, Infectious and Tropical Diseases Department, Paris, France; Faculté de Médecine, Université Pierre et Marie Curie, Paris, France.
⁶ AP-HP, Hôpital Pitié-Salpêtrière, Centre National de Référence des Mycobactéries et de la Résistance des Mycobactéries aux Antituberculeux, Bactériologie-Hygiène, Paris, France; INSERM, U1135, Centre d'Immunologie et des Maladies Infectieuses, CIMI, team E13 (Bacteriology), Paris, France; Sorbonne Universités, UPMC Univ Paris 06, CR7, Centre d'Immunologie et des Maladies Infectieuses, CIMI, team E13 (Bacteriology), Paris, France.

PMID: 25835101
DOI: 10.1016/j.ijid.2015.03.019

Abstract

We report herein a case of bacteremic ascitic fluid infection in a liver transplant patient caused by a strain of Yersinia pseudotuberculosis serogroup I that lost the yersiniabactin core. The patient's outcome was favorable after a combined therapy with a third-generation cephalosporin and gentamicin.

Keywords: Ascitic fluid infection; Bacteremia; Hepatic cirrhosis; Liver transplant; Third-generation cephalosporin; Yersinia pseudotuberculosis.

Publication types

Case Reports

MeSH terms

Anti-Bacterial Agents / therapeutic use
Ascitic Fluid / microbiology*
Bacteremia / diagnosis*
Bacteremia / drug therapy
Bacteremia / etiology
Cephalosporins / therapeutic use
Drug Therapy, Combination
Gentamicins / therapeutic use
Humans
Liver Transplantation*
Male
Middle Aged
Treatment Outcome
Yersinia pseudotuberculosis / isolation & purification*
Yersinia pseudotuberculosis Infections / diagnosis*
Yersinia pseudotuberculosis Infections / drug therapy

Substances

Anti-Bacterial Agents
Cephalosporins
Gentamicins