Thiotaurine protects mouse cerebellar granule neurons from potassium deprivation-induced apoptosis by inhibiting the activation of caspase-3

Adv Exp Med Biol. 2015:803:513-23. doi: 10.1007/978-3-319-15126-7_41.

Authors

Jessica Dragotto¹, Elisabetta Capuozzo, Mario Fontana, Armando Curci, Maria Teresa Fiorenza, Sonia Canterini

Affiliation

¹ Section of Neuroscience, Department of Psychology, "Daniel Bovet" Neurobiology Research Center, "Sapienza" University of Rome, Via dei Sardi 70, 00185, Rome, Italy.

PMID: 25833523
DOI: 10.1007/978-3-319-15126-7_41

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Apoptosis / drug effects*
Caspase 3 / metabolism*
Caspase Inhibitors / pharmacology
Cells, Cultured
Cerebellum / cytology
Cerebellum / drug effects
Cytoprotection / drug effects
Enzyme Activation / drug effects
Mice
Neurons / drug effects*
Neurons / pathology
Neurons / physiology
Potassium / pharmacology
Potassium Deficiency / pathology*
Taurine / analogs & derivatives*
Taurine / pharmacology

Substances

Caspase Inhibitors
Taurine
Caspase 3
thiotaurine
Potassium