An Implantable RFID Sensor Tag toward Continuous Glucose Monitoring

IEEE J Biomed Health Inform. 2015 May;19(3):910-9. doi: 10.1109/JBHI.2015.2415836. Epub 2015 Mar 23.

Abstract

This paper presents a wirelessly powered implantable electrochemical sensor tag for continuous blood glucose monitoring. The system is remotely powered by a 13.56-MHz inductive link and utilizes an ISO 15693 radio frequency identification (RFID) standard for communication. This paper provides reliable and accurate measurement for changing glucose level. The sensor tag employs a long-term glucose sensor, a winding ferrite antenna, an RFID front-end, a potentiostat, a 10-bit sigma-delta analog to digital converter, an on-chip temperature sensor, and a digital baseband for protocol processing and control. A high-frequency external reader is used to power, command, and configure the sensor tag. The only off-chip support circuitry required is a tuned antenna and a glucose microsensor. The integrated chip fabricated in SMIC 0.13-μm CMOS process occupies an area of 1.2 mm ×2 mm and consumes 50 μW. The power sensitivity of the whole system is -4 dBm. The sensor tag achieves a measured glucose range of 0-30 mM with a sensitivity of 0.75 nA/mM.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Blood Glucose / analysis*
  • Extracellular Fluid / chemistry
  • Male
  • Monitoring, Physiologic / instrumentation*
  • Prostheses and Implants*
  • Prosthesis Design
  • Radio Frequency Identification Device*
  • Rats
  • Rats, Wistar
  • Sensitivity and Specificity
  • Wireless Technology / instrumentation*

Substances

  • Blood Glucose