Whole-Genome Sequence of Clostridium botulinum A2B3 87, a Highly Virulent Strain Involved in a Fatal Case of Foodborne Botulism in Italy

Francesco Giordani; Silvia Fillo; Anna Anselmo; Anna Maria Palozzi; Antonella Fortunato; Bernardina Gentile; Valentina Pittiglio; Ferdinando Spagnolo; Fabrizio Anniballi; Alfonsina Fiore; Bruna Auricchio; Dario De Medici; Florigio Lista

doi:10.1128/genomeA.00237-15

Whole-Genome Sequence of Clostridium botulinum A2B3 87, a Highly Virulent Strain Involved in a Fatal Case of Foodborne Botulism in Italy

Genome Announc. 2015 Mar 26;3(2):e00237-15. doi: 10.1128/genomeA.00237-15.

Affiliations

¹ Histology and Molecular Biology Section Army Medical and Veterinary Research Center, Rome, Italy.
² National Reference Center for Botulism, Department of Veterinary Public Health and Food Safety, Istituto Superiore di Sanità (ISS), Rome, Italy.
³ Histology and Molecular Biology Section Army Medical and Veterinary Research Center, Rome, Italy romano.lista@gmail.com.

Abstract

Here, we report the genome sequence of a rare bivalent strain of Clostridium botulinum, A2B3 87. The strain was isolated from a foodborne botulism case that occurred in Italy in 1995. The case was characterized by rapid evolution of the illness and failure of conventional treatments.