Chemical proteomics versus leishmaniasis

Michael Ehrmann; Farnusch Kaschani; Markus Kaiser

doi:10.1016/j.chembiol.2015.03.001

Chemical proteomics versus leishmaniasis

Chem Biol. 2015 Mar 19;22(3):309-10. doi: 10.1016/j.chembiol.2015.03.001.

Authors

Michael Ehrmann¹, Farnusch Kaschani², Markus Kaiser³

Affiliations

¹ Department of Microbiology, University of Duisburg-Essen, Center for Medical Biotechnology, Faculty of Biology, 45117 Essen, Germany.
² Department of Chemical Biology, University of Duisburg-Essen, Center for Medical Biotechnology, Faculty of Biology, 45117 Essen, Germany.
³ Department of Chemical Biology, University of Duisburg-Essen, Center for Medical Biotechnology, Faculty of Biology, 45117 Essen, Germany. Electronic address: markus.kaiser@uni-due.de.

PMID: 25794432
DOI: 10.1016/j.chembiol.2015.03.001

Abstract

In this issue of Chemistry & Biology, Wright et al. (2015) describe an elegant approach to evaluating substrates and the drug target potential of Leishmania donovani N-myristoyltransferase (NMT) using a technically simple and straightforward chemical proteomics approach.

Publication types

Comment

MeSH terms

Acyltransferases / metabolism*
Animals
Humans
Leishmania donovani / metabolism*
Protozoan Proteins / metabolism*

Substances

Protozoan Proteins
Acyltransferases