Case records of the Massachusetts General Hospital. Case 9-2015. A 31-year-old man with personality changes and progressive neurologic decline

N Engl J Med. 2015 Mar 19;372(12):1151-62. doi: 10.1056/NEJMcpc1409839.
No abstract available

Publication types

  • Case Reports
  • Clinical Conference
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Atrophy
  • Fatal Outcome
  • Frontal Lobe / pathology*
  • Humans
  • Male
  • Neuroimaging
  • Personality Disorders / etiology
  • Pick Disease of the Brain / genetics
  • Pick Disease of the Brain / pathology*
  • Pick Disease of the Brain / psychology
  • Point Mutation
  • Temporal Lobe / pathology*
  • tau Proteins / genetics*
  • tau Proteins / immunology

Substances

  • MAPT protein, human
  • tau Proteins