Synchronous reconstruction of bilateral osteoradionecrosis of the mandible using a single fibular osteocutaneous flap in patients with nasopharyngeal carcinoma

Head Neck. 2016 Apr:38 Suppl 1:E607-12. doi: 10.1002/hed.24049. Epub 2015 Jul 6.

Abstract

Background: The reconstruction of bilateral osteoradionecrosis (ORN) of mandibular defects using a single free bone flap is rarely performed because extensively radiated neck tissue with severe fibrosis is usually unsuitable for vascularized reconstruction.

Methods: Thirty-one patients with nasopharyngeal carcinoma (NPC) underwent bilateral reconstruction of advanced ORN in the mandible using a single fibular osteocutaneous flap. Clinical factors associated with the operation were assessed, including classification of mandible defects, types of recipient vessels, perioperative complications, and postoperative outcomes.

Results: All of the fibular osteocutaneous flaps survived completely, with the exception of 1 inner skin paddle that presented partial necrosis in a reconstruction of through-and-through defects. All patients experienced an improvement in cosmetic results 6 months after the reconstruction, whereas 23 patients experienced improved mouth opening compared to the preoperative condition.

Conclusion: Advanced bilateral ORN in patients with NPC could be synchronously reconstructed with a single fibular osteocutaneous flap. © 2015 Wiley Periodicals, Inc. Head Neck 38: E-E, 2016.

Keywords: bilateral osteoradionecrosis; fibular osteocutaneous flap; mandible; nasopharyngeal carcinoma; synchronous reconstruction.

MeSH terms

  • Adolescent
  • Adult
  • Carcinoma / surgery*
  • Female
  • Fibula / transplantation*
  • Free Tissue Flaps / transplantation
  • Humans
  • Male
  • Mandible / surgery*
  • Middle Aged
  • Nasopharyngeal Carcinoma
  • Nasopharyngeal Neoplasms / surgery*
  • Osteoradionecrosis / surgery*
  • Plastic Surgery Procedures*
  • Prospective Studies
  • Young Adult