The genus Anthrenus, is in the subfamily Megatominae. It is relatively speciose within family Dermestidae and currently contains ca. 250 valid taxa which have been grouped within 10 subgenera. Most of the species are found in the Palearctic ecozone. Anthrenus (Helocerus) cechovskyi Háva & Kadej, sp. nov. is described from Nepal. The habitus, antenna, genitalia are illustrated and compared with related species. A key to the known species from the Nepal is presented. Only seven species of Dermestidae have been recorded from Nepal so far. Newly described species is the first species of subgenus Helocerus which have been found in Nepal. Further study of Dermestidae of Nepal and adjacent countries is required.