The Prostate Cancer DREAM Challenge: A Community-Wide Effort to Use Open Clinical Trial Data for the Quantitative Prediction of Outcomes in Metastatic Prostate Cancer

Kald Abdallah; Charles Hugh-Jones; Thea Norman; Stephen Friend; Gustavo Stolovitzky

doi:10.1634/theoncologist.2015-0054

The Prostate Cancer DREAM Challenge: A Community-Wide Effort to Use Open Clinical Trial Data for the Quantitative Prediction of Outcomes in Metastatic Prostate Cancer

Oncologist. 2015 May;20(5):459-60. doi: 10.1634/theoncologist.2015-0054. Epub 2015 Mar 16.

Authors

Kald Abdallah¹, Charles Hugh-Jones², Thea Norman², Stephen Friend², Gustavo Stolovitzky²

Affiliations

¹ Project Data Sphere, Raleigh, North Carolina, USA; Sanofi US, Bridgewater, New Jersey, USA; Sage Bionetworks, Seattle, Washington, USA; IBM T.J. Watson Research Center, Yorktown Heights, New York, USA; Icahn School of Medicine at Mount Sinai, New York, New York, USA kald.abdallah@projectdatasphere.org.
² Project Data Sphere, Raleigh, North Carolina, USA; Sanofi US, Bridgewater, New Jersey, USA; Sage Bionetworks, Seattle, Washington, USA; IBM T.J. Watson Research Center, Yorktown Heights, New York, USA; Icahn School of Medicine at Mount Sinai, New York, New York, USA.

Abstract

Project Data Share and Sage Bionetworks/DREAM are launching the Prostate Cancer DREAM Challenge to improve a predictive model of disease progression and treatment toxicity in prostate cancer using historical trial data. Predictions identified through this challenge have the potential to translate into reduced trial redundancy, better clinical decision tools, and improved patient outcomes. The challenge launches on March 16, 2015.

Publication types

Editorial

MeSH terms

Clinical Trials as Topic
Humans
Male
Neoplasm Metastasis
Prostatic Neoplasms / epidemiology*
Prostatic Neoplasms / genetics
Prostatic Neoplasms / pathology
Prostatic Neoplasms / therapy*
Treatment Outcome