Isolated neurosarcoidosis mimicking intracranial tumours - Analysis of 3 cases

Abstract

Isolated neurosarcoidosis (INS), as a disease of low prevalence, is commonly overlooked in differential diagnosis, and its discovery on histopathological examination usually comes as a surprise. Preoperative diagnosis is difficult because the clinical picture of INS is non-specific. Its symptoms depend on the location of the lesions, and the MRI results are similar to those found in meningiomas or optic nerve gliomas. Although up to 5% of all sarcoidosis patients present with neurological symptoms, those with INS are exceptionally infrequently encountered. Three cases of INS are presented here, analysing their clinical course and radiological images, in order to determine characteristic traits that might lead to a correct diagnosis.

Keywords: Brain tumour diagnosis; Diagnóstico de tumour cerebral; Glioma del nervio óptico; Isolated neurosarcoidosis; Meningioma; Neurosarcoidosis MRI; Neurosarcoidosis RM; Neurosarcoidosis aislada; Neurosarcoidosis clinical manifestations; Neurosarcoidosis manifestaciones clínicas; Optic nerve glioma.