Effect of depressive and anxiety symptoms during pregnancy on risk of obstetric interventions

J Obstet Gynaecol Res. 2015 Jul;41(7):1040-8. doi: 10.1111/jog.12683. Epub 2015 Mar 15.

Abstract

Aim: The effect of prenatal mental health on the risk of obstetric interventions is unclear. The present study examined the associations between depressive and anxiety symptoms in the second and third trimesters and mode of delivery, epidural use and labor induction in a large community-based pregnancy cohort, in Alberta, Canada.

Material and methods: Women who had singleton pregnancies, delivered in hospital, and had medical data were selected (n = 2825). Obstetric intervention data were obtained from the medical records, and depressive and anxiety symptoms were measured by the Edinburgh Postnatal Depression Scale and the Spielberger State Anxiety Inventory. Data were evaluated with multivariate multinomial and logistic regression analyses using a hierarchical modeling.

Results: After accounting for factors known to increase the risk of each intervention, including demographic variables, smoking, hospital site, gestational age, previous history of cesarean delivery, prepregnancy body mass index, assisted conception, and antepartum risk score, the only mental health variable associated with obstetric interventions was depressive symptoms in the third trimester, which increased the risk of emergency cesarean delivery (adjusted odds ratio, 2.04; 95% confidence interval, 1.26-3.29). No associations were found between antenatal depressive and anxiety symptoms and other obstetric interventions.

Conclusion: The present findings support an association between depressive symptoms and adverse obstetric outcomes and suggest that anxiety and depression may have different effects on obstetric outcomes. Understanding the mechanism in which depression increases the risk of emergency cesarean birth needs further research.

Keywords: cesarean delivery; obstetric interventions; prenatal mental health; risk factors.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Alberta / epidemiology
  • Anxiety / complications*
  • Anxiety / epidemiology
  • Cesarean Section / adverse effects
  • Cesarean Section / psychology
  • Cohort Studies
  • Depression / complications*
  • Depression / epidemiology
  • Depression, Postpartum / epidemiology
  • Female
  • Humans
  • Longitudinal Studies
  • Obstetric Labor Complications / epidemiology
  • Obstetric Labor Complications / psychology*
  • Obstetric Labor Complications / surgery
  • Pregnancy
  • Pregnancy Complications / epidemiology
  • Pregnancy Complications / psychology*
  • Pregnancy Complications / surgery
  • Pregnancy Outcome
  • Pregnancy Trimester, Second
  • Pregnancy Trimester, Third
  • Prevalence
  • Psychiatric Status Rating Scales
  • Risk Factors
  • Young Adult