Biomolecular systems for information processing have recently received great attention in the general framework of unconventional computing. While DNA biocomputing systems have been studied by many researchers and have already reached a high level of complexity, enzyme-based cascades mimicking Boolean logic operations are a relatively new subfield that is rapidly progressing. The present paper reviews recent progress in the enzyme-based information processing systems and suggests applications in biosensing, rather than computation. Specific examples of enzyme-based logic systems are discussed to introduce readers to this rapidly developing research area.
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